Dr Orla Slattery

Lecturer and Researcher in medical science and fish health
+353 (0)91 742554

I hold an Honours degree in Industrial Biochemistry (2003) and a PhD (2008) from University of Limerick. My PhD research focussed on purifying and crystallising the membrane protein complex cytochrome caa3-oxidase from Thermus thermophilus using the lipidic cubic phase method of crystallisation. I was a postdoctoral researcher at the University of Frankfurt, Germany where I researched molecular mechanisms of antibiotic resistance. I used structural and molecular biology techniques as well biochemical methods to research tripartite antibiotic resistance complexes including AcrAB-TolC from Escherichia coli and VexEF-TolC from Vibrio vulnificus. After a short stint as a Medical Writer in Frankfurt, I joined GMIT in 2015, lecturing in Biochemisty in the Department of Biopharmaceutical and Medical Science. My current research with the MFRC’s Fish Health and Molecular group uses proteomic and molecular techniques to investigate host-pathogen interactions and biomarkers, particularly those relating to fish health. Additionally, our research includes the purification and functional analysis of antimicrobial peptides from marine organisms.

Projects

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The aim of the project is to identify and characterise antimicrobial peptides from a range of seaweed species and is particularly focused on the functional effect of the peptides extracted from seaweed products.
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MFRC researchers are collaborating with IT Sligo to investigate antimicrobial peptides in Atlantic Salmon.
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The ADIOS project aims are to advance our understanding of amoebic gill disease affecting Atlantic salmon (Salmo salar) using a range of molecular and microbiological techniques
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This MSc project (student Daniel Brady) was co-funded by GMIT and the National Parks and Wildlife Service.